Sibutramine active principle of Sibus, Biomag, Redulip, Saciette, Sibutram, Sigran, Slenfig, Vazy, Nolipo, Meridia, Reductilreduce calorie intake by inhibiting appetite and increase satiety and raises metabolism, increasing the body's calorie consumption.
Sibutramine acts in the hypothalamus (in the brain) which is responsible for anxiety control and hunger. So is classified as Moderator of appetite being administered orally for the treatment of obesity.(Recommended for weight loss and maintenance of weight lost)
News in the press
In 2011, the United Kingdom made an extensive review of the medical literature and analyzed studies, with a minimum duration of 1 year, which treated obese patients with weight loss diet associated with the medicine Sibutramine (Sibus, Biomag, Redulip, Saciette, Sibutram, Sigran, Slenfig, Vazy, Nolipo, Meridia, Reductil).
In the studies reviewed, associate Sibutramine (Sibus, Biomag, Redulip, Saciette, Sibutram, Sigran, Slenfig, Vazy, Nolipo, Meridia, Reductil) to a low-calorie diet showed weight loss, gradual and constant, during one year (duration of treatment).
Statistically significant beneficial effects were found in levels of HDL cholesterol and triglycerides.
Bythe other hand, was an increase in diastolic blood pressure levels.
Contraindications
Sibutramine is contraindicated in cases of:
- Hypertension is not sufficiently controlled.
- Psychiatric conditions as bulimia nervosa, anorexia nervosa, depression, or preexisting mania.
- Hypersensitivity to the drug
- Patients below 18 years of age.
- Concomitant treatment with monoamine Oxidase inhibitors (MAO), antidepressants or other centrally active drugs.
- Pulmonary hypertension.
- Existing lesions in heart valves, coronary heart disease, congestive heart failure, serious arrhythmia and myocardial infarction.
- Stroke or transient ischemic attack.
- Hyperthyroidism.
- Closed angle Glaucoma.
- Seizure problems.
- Enlargement of the prostate gland with urinary retention.
- Pheochromocytoma.
- Pregnant or lactating women.
Side effects of sibutramine
The most common side effects are:
In some patients sibutramine can raise blood pressure. In this way, all treated with sibutramine should go through regular monitoring of the pressure.
The following side effects are uncommon but serious and require immediate medical attention: cardiac arrhythmia, paresthesia, mental and mood changes.
Symptoms that require urgent medical attention are: seizure, problem urinating, chest pain, hemiplegia, abnormal vision, Dyspnea and edema.
Dosage:
1 tablet in the morning before breakfast.
(used up to 24 months)
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7 Key questions about sibutramine
1. What is the difference between manipulated and industrialized Sibutramine?
It is not recommended the consumption of compounding, first because often it is mixed with other substances such as amphetamines, always harmful to health and second that the quality and origin of sibutramine is doubtful.
The industrialized medicine is always the best option.
2. sibutramine can be mixed with other substances?
Although not very common, some doctors suggest the use of sibutramine with other substances such as amphetamines. Look for escape of these combinations and talk to your doctor about the necessity of effective mixing with other substances.
3. can I take Sibutramine and drink alcohol?
Sibutramine is a medicine neurological action and, therefore, alcoholic beverages may not be consumed during treatment.
In addition to the adverse reactions alcohol cuts the effect of the remedy.
4. can I take Sibutramine during pregnancy or breast-feeding?
It is forbidden to use the drug during pregnancy and breastfeeding may cause serious risks to the baby.
5. Sibutramine cause impotence or changes the sexual appetite?
No cases of impotence with the use of sibutramine, but can occur in either the increase and decrease sexual appetite during its use.
6. When you stop taking sibutramine engordarei twice?
During the use of sibutramine is important as it is made a dietary re-education so that to stop the use of the medicine, you do not eat compulsively. Enjoy the time you are taking the remedy, to work their head and body in search of a correct power supply.
7. Sibutramine cause abdominal pain or disrupts the menstruation?
Although not common, the use of the substance can deregulate the cycle and the menstrual flow, as well as cramping and abdominal pain may occur.
Ban
It is not today that we see news in the media talking about the prohibition of sibutramine in Europe, USA and Brazil, but what is and what is not true among so many news?
It is true that in Europe the sibutramine has been banned.
Since January 25, 2010 the marketing of the remedy is prohibited by European Medicines Agency EMEA, because it increases the risk of stroke and heart attack.
